
If a girl teases you, that means she likes you! Unfortunately, Akiteru knows from experience that isn't the case. Because every girl he interacts with shows him nothing but scorn, and he's not scored a single date from it! Luckily, he's more concerned with securing a spot for him and his game-development buddies at his uncle's business. But when his uncle throws him a condition that involves playing the part of his daughter's boyfriend, Akiteru has no choice but to take it. What will his best ...
Tomodachi no Imouto ga Ore ni dake Uzai aired on TV Asahi's NUMAnimation block.
A lighthearted romantic comedy about a guy fake-dating his uncle's daughter while enduring relentless teasing from his best friend's younger sister. Expect playful tsundere dynamics, school setting hijinks, and mild fan service without crossing into explicit territory.
My Friend's Little Sister Has It In for Me! has 12 episodes.
My Friend's Little Sister Has It In for Me! is currently finished airing.
My Friend's Little Sister Has It In for Me! was produced by Blade.
My Friend's Little Sister Has It In for Me! aired Oct 5, 2025 to Dec 21, 2025.
My Friend's Little Sister Has It In for Me! is based on a Light novel.
A lighthearted romantic comedy about a guy fake-dating his uncle's daughter while enduring relentless teasing from his best friend's younger sister. Expect playful tsundere dynamics, school setting hijinks, and mild fan service without crossing into explicit territory.
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Kohinata, Iroha
Main
CV: Suzushiro, Sayumi

Ooboshi, Akiteru
Main
CV: Ishiya, Haruki

Tsukinomori, Mashiro
Main
CV: Kusunoki, Tomori

Kageishi, Sumire
Supporting
CV: Hanazawa, Kana

Kageishi, Midori
Supporting
CV: Kondou, Reina

Kiraboshi, Kanaria
Supporting
CV: Tamura, Yukari

Kishida
Supporting
CV: Kohana Lam

Kohinata, Ozuma
Supporting
CV: Saitou, Souma

Kuwahara
Supporting
CV: Sasaki, Hitomi

Nagai
Supporting
CV: Itou, Sayaka

Otoi
Supporting
CV: Tadokoro, Azusa

Suzuki, Takeshi
Supporting
CV: Yamaguchi, Tomohiro

Tachibana, Asagi
Supporting
CV: Kikuchi, Sayaka

Tomosaka, Sasara
Supporting
CV: Hasegawa, Ikumi

Tsukinomori, Makoto
Supporting
CV: Konishi, Katsuyuki

Watanabe
Supporting
CV: Mizuki, Rin

Yamada
Supporting
CV: Miyamoto, Yume
12 episodes
Ranked higher than 61% of all anime on AniTome (out of 19,551)
More popular than 88% of all anime